How To Deal With Side Effects From Weight Loss Medications

Medications that help to lower blood sugar levels and promote weight loss have emerged as a promising new option for people who struggle with their weight. These drugs, known as GLP-1 agonists, have proven to be very effective. However, like many medications, they may come with gastrointestinal (GI) side effects that can impact a patient’s comfort and adherence.

With the right strategies and a well-informed approach, managing these side effects is possible. You too can achieve a successful voyage towards a healthier weight. 

Side effects + tips to address them

Nearly half of the people who take a GLP-1 weight management medication experience one or more GI side effects. The most commonly reported ones are nausea and vomiting, acid reflux, bloating, stomach cramps, diarrhea and/or constipation. While these symptoms are generally mild and temporary, they may make it difficult to stick with the treatment.

Most of these medications are prescribed at a lower dose and adjusted slowly over time to help your body adjust. Symptoms typically decrease as your body adapts to the medication and your eating habits change. Side effects may resolve initially but could occur again with a dose increase.

To get started on the right path, here are some general tips for minimizing these side effects. 

If you’re using weight loss drugs, here’s how to minimize risks:

1. Stay Hydrated & Eat Fiber

• Helps with digestive issues (diarrhea, constipation).

• Prevents dehydration, especially with stimulant-based meds.

2. Monitor Blood Pressure & Heart Rate

• If taking Phentermine, check your BP regularly.

• Avoid caffeine to prevent heart palpitations.

3. Take Multivitamins (For Fat Blockers Like Orlistat)

• Prevents vitamin deficiencies from fat malabsorption.

4. Avoid Alcohol & Processed Foods

• Some medications interact poorly with alcohol.

• Junk food can worsen digestive side effects.

5. Consult a Doctor Before Use

• Not everyone should take weight loss meds (e.g., pregnant women, heart patients).

• A doctor can recommend safer alternatives if side effects are severe.

As you follow the path to a lower weight, keep track of your symptoms and share any concerns with your health care provider. Communicate regularly to ensure they can make adjustments to your dosage. While GLP-1 agonists offer a promising avenue for weight loss, managing the side effects will be a key aspect to improving your overall experience.